Abstract
Ambient mass spectrometry-mass spectrometric analysis with no or minimal
effort for sample preparation-has experienced a very rapid development
during the last 5 years, with many different methods now available for
ionization. Here, we review its range of applications, the hurdles
encountered for its quantitative use, and the proposed mechanisms for
ion formation. Clearly, more effort needs to be put into investigation
of matrix effects, into defining representative sampling of
heterogeneous materials, and into understanding and controlling the
underlying ionization mechanisms. Finally, we propose a concept to
reduce the number of different acronyms describing very similar
embodiments of ambient mass spectrometry. (J Am Soc Mass Spectrom 2009,
20, 1947-1963) (C) 2009 American Society for Mass Spectrometry
| Original language | English |
|---|---|
| Pages (from-to) | 1947-1963 |
| Journal | Journal of the American Society for Mass Spectrometry |
| State | Published - Nov 2009 |
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Cite this
Chen, H., Gamez Goytia, G., & Zenobi, R. (2009). What Can We Learn from Ambient Ionization Techniques? Journal of the American Society for Mass Spectrometry, 1947-1963.