Weight loss can lead to resolution of Gastroesophageal Reflux Disease symptoms: A prospective intervention trial

M Singh; Jae Hoon Lee; N Gupta; S Gaddam; B K Smith; S B Wani; D K Sullivan; A Rastogi; A Bansal; J E Donnelly; P Sharma

Weight loss can lead to resolution of Gastroesophageal Reflux Disease symptoms: A prospective intervention trial

M Singh, Jae Hoon Lee, N Gupta, S Gaddam, B K Smith, S B Wani, D K Sullivan, A Rastogi, A Bansal, J E Donnelly, P Sharma

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Abstract

OBJECTIVE: Weight gain is an important risk factor for gastroesophageal reflux disease (GERD); however, whether weight loss can lead to resolution of GERD symptoms is not clear. Our aim was to measure the impact of weight loss on GERD symptoms. DESIGN AND METHODS: In a prospective cohort study at a tertiary referral center, overweight/obese subjects (BMI 25-39.9 kg/m2) were enrolled in a structured weight loss program. Weight loss strategies included dietary modifications, increased physical activity and behavioral changes. At baseline and at 6 months, BMI and waist circumference were measured and all participants completed a validated reflux disease questionnaire. RESULTS: A total of 332 adult subjects, mean age 46 years and 66% women were prospectively enrolled. At baseline, the mean body weight, BMI, and waist circumference were 101 (±18) kg, 35 (±5) kg/m2 and 103 (±13) cm. At 6 months, majority of the subjects (97%) lost weight (average weight loss: 13 ± 7.7 kg) and as compared wi

Original language	English
Pages (from-to)	284–290
Journal	Obesity
State	Published - 2013

Cite this

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title = "Weight loss can lead to resolution of Gastroesophageal Reflux Disease symptoms: A prospective intervention trial",

abstract = "OBJECTIVE: Weight gain is an important risk factor for gastroesophageal reflux disease (GERD); however, whether weight loss can lead to resolution of GERD symptoms is not clear. Our aim was to measure the impact of weight loss on GERD symptoms. DESIGN AND METHODS: In a prospective cohort study at a tertiary referral center, overweight/obese subjects (BMI 25-39.9 kg/m2) were enrolled in a structured weight loss program. Weight loss strategies included dietary modifications, increased physical activity and behavioral changes. At baseline and at 6 months, BMI and waist circumference were measured and all participants completed a validated reflux disease questionnaire. RESULTS: A total of 332 adult subjects, mean age 46 years and 66% women were prospectively enrolled. At baseline, the mean body weight, BMI, and waist circumference were 101 (±18) kg, 35 (±5) kg/m2 and 103 (±13) cm. At 6 months, majority of the subjects (97%) lost weight (average weight loss: 13 ± 7.7 kg) and as compared wi",

author = "M Singh and Lee, {Jae Hoon} and N Gupta and S Gaddam and Smith, {B K} and Wani, {S B} and Sullivan, {D K} and A Rastogi and A Bansal and Donnelly, {J E} and P Sharma",

year = "2013",

language = "English",

pages = "284–290",

journal = "Obesity",

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TY - JOUR

T1 - Weight loss can lead to resolution of Gastroesophageal Reflux Disease symptoms: A prospective intervention trial

AU - Singh, M

AU - Lee, Jae Hoon

AU - Gupta, N

AU - Gaddam, S

AU - Smith, B K

AU - Wani, S B

AU - Sullivan, D K

AU - Rastogi, A

AU - Bansal, A

AU - Donnelly, J E

AU - Sharma, P

PY - 2013

Y1 - 2013

N2 - OBJECTIVE: Weight gain is an important risk factor for gastroesophageal reflux disease (GERD); however, whether weight loss can lead to resolution of GERD symptoms is not clear. Our aim was to measure the impact of weight loss on GERD symptoms. DESIGN AND METHODS: In a prospective cohort study at a tertiary referral center, overweight/obese subjects (BMI 25-39.9 kg/m2) were enrolled in a structured weight loss program. Weight loss strategies included dietary modifications, increased physical activity and behavioral changes. At baseline and at 6 months, BMI and waist circumference were measured and all participants completed a validated reflux disease questionnaire. RESULTS: A total of 332 adult subjects, mean age 46 years and 66% women were prospectively enrolled. At baseline, the mean body weight, BMI, and waist circumference were 101 (±18) kg, 35 (±5) kg/m2 and 103 (±13) cm. At 6 months, majority of the subjects (97%) lost weight (average weight loss: 13 ± 7.7 kg) and as compared wi

AB - OBJECTIVE: Weight gain is an important risk factor for gastroesophageal reflux disease (GERD); however, whether weight loss can lead to resolution of GERD symptoms is not clear. Our aim was to measure the impact of weight loss on GERD symptoms. DESIGN AND METHODS: In a prospective cohort study at a tertiary referral center, overweight/obese subjects (BMI 25-39.9 kg/m2) were enrolled in a structured weight loss program. Weight loss strategies included dietary modifications, increased physical activity and behavioral changes. At baseline and at 6 months, BMI and waist circumference were measured and all participants completed a validated reflux disease questionnaire. RESULTS: A total of 332 adult subjects, mean age 46 years and 66% women were prospectively enrolled. At baseline, the mean body weight, BMI, and waist circumference were 101 (±18) kg, 35 (±5) kg/m2 and 103 (±13) cm. At 6 months, majority of the subjects (97%) lost weight (average weight loss: 13 ± 7.7 kg) and as compared wi

M3 - Article

SP - 284

EP - 290

JO - Obesity

JF - Obesity

ER -

Weight loss can lead to resolution of Gastroesophageal Reflux Disease symptoms: A prospective intervention trial

Abstract

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