TY - JOUR
T1 - Visible-light-promoted intramolecular C-H amination in aqueous solution
T2 - Synthesis of carbazoles
AU - Yang, Lizheng
AU - Zhang, Yipin
AU - Zou, Xiaodong
AU - Lu, Hongjian
AU - Li, Guigen
N1 - Funding Information:
We would like to acknowledge financial support from the National Natural Science Foundation of China (No. 21332005, 21472085), and the Fundamental Research Funds for the Central Universities (No. 020514380114).
Publisher Copyright:
© The Royal Society of Chemistry 2018.
PY - 2018
Y1 - 2018
N2 - An effective and operationally simple protocol is reported for the synthesis of versatile carbazoles. With water as a co-solvent, visible-light rather than various metals is used to facilitate the conversion of readily available 2-azidobiphenyls under mild conditions. Various functionalized bioactive natural alkaloids, such as glycoborine, clausine C, clausine L, clausine H and clauszoline K, were synthesized efficiently with nitrogen as a sole byproduct. The reaction could be performed in water, acidic or alkaline buffer solutions, showing its potential for applications in biochemistry.
AB - An effective and operationally simple protocol is reported for the synthesis of versatile carbazoles. With water as a co-solvent, visible-light rather than various metals is used to facilitate the conversion of readily available 2-azidobiphenyls under mild conditions. Various functionalized bioactive natural alkaloids, such as glycoborine, clausine C, clausine L, clausine H and clauszoline K, were synthesized efficiently with nitrogen as a sole byproduct. The reaction could be performed in water, acidic or alkaline buffer solutions, showing its potential for applications in biochemistry.
UR - http://www.scopus.com/inward/record.url?scp=85044247886&partnerID=8YFLogxK
U2 - 10.1039/c7gc03392c
DO - 10.1039/c7gc03392c
M3 - Article
AN - SCOPUS:85044247886
VL - 20
SP - 1362
EP - 1366
JO - Green Chemistry
JF - Green Chemistry
SN - 1463-9262
IS - 6
ER -