Visible-light-promoted intramolecular C-H amination in aqueous solution: synthesis of carbazoles

Lizheng Yang; Yipin Zhang; Xiaodong Zou; Hongjian Lu; Guigen Li

Visible-light-promoted intramolecular C-H amination in aqueous solution: synthesis of carbazoles

Lizheng Yang, Yipin Zhang, Xiaodong Zou, Hongjian Lu, Guigen Li

Chemistry and Biochemistry

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29 Scopus citations

Abstract

An effective and operationally simple protocol is reported for the synthesis of versatile carbazoles. With water as a co-solvent, visible-light rather than various metals is used to facilitate the conversion of readily available 2-azidobiphenyls under mild conditions. Various functionalized bioactive natural alkaloids, such as glycoborine, clausine C, clausine L, clausine H and clauszoline K, were synthesized efficiently with nitrogen as a sole byproduct. The reaction could be performed in water, acidic or alkaline buffer solutions, showing its potential for applications in biochemistry.

Original language	English
Pages (from-to)	1362-1366
Journal	Default journal
State	Published - 2018

Cite this

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title = "Visible-light-promoted intramolecular C-H amination in aqueous solution: synthesis of carbazoles",

abstract = "An effective and operationally simple protocol is reported for the synthesis of versatile carbazoles. With water as a co-solvent, visible-light rather than various metals is used to facilitate the conversion of readily available 2-azidobiphenyls under mild conditions. Various functionalized bioactive natural alkaloids, such as glycoborine, clausine C, clausine L, clausine H and clauszoline K, were synthesized efficiently with nitrogen as a sole byproduct. The reaction could be performed in water, acidic or alkaline buffer solutions, showing its potential for applications in biochemistry.",

author = "Lizheng Yang and Yipin Zhang and Xiaodong Zou and Hongjian Lu and Guigen Li",

note = "Funding Information: We would like to acknowledge financial support from the National Natural Science Foundation of China (No. 21332005, 21472085), and the Fundamental Research Funds for the Central Universities (No. 020514380114). Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2018.",

year = "2018",

language = "English",

pages = "1362--1366",

journal = "Default journal",

issn = "1463-9262",

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TY - JOUR

T1 - Visible-light-promoted intramolecular C-H amination in aqueous solution: synthesis of carbazoles

AU - Yang, Lizheng

AU - Zhang, Yipin

AU - Zou, Xiaodong

AU - Lu, Hongjian

AU - Li, Guigen

N1 - Funding Information: We would like to acknowledge financial support from the National Natural Science Foundation of China (No. 21332005, 21472085), and the Fundamental Research Funds for the Central Universities (No. 020514380114). Publisher Copyright: © The Royal Society of Chemistry 2018.

PY - 2018

Y1 - 2018

N2 - An effective and operationally simple protocol is reported for the synthesis of versatile carbazoles. With water as a co-solvent, visible-light rather than various metals is used to facilitate the conversion of readily available 2-azidobiphenyls under mild conditions. Various functionalized bioactive natural alkaloids, such as glycoborine, clausine C, clausine L, clausine H and clauszoline K, were synthesized efficiently with nitrogen as a sole byproduct. The reaction could be performed in water, acidic or alkaline buffer solutions, showing its potential for applications in biochemistry.

AB - An effective and operationally simple protocol is reported for the synthesis of versatile carbazoles. With water as a co-solvent, visible-light rather than various metals is used to facilitate the conversion of readily available 2-azidobiphenyls under mild conditions. Various functionalized bioactive natural alkaloids, such as glycoborine, clausine C, clausine L, clausine H and clauszoline K, were synthesized efficiently with nitrogen as a sole byproduct. The reaction could be performed in water, acidic or alkaline buffer solutions, showing its potential for applications in biochemistry.

M3 - Article

AN - SCOPUS:85044247886

SN - 1463-9262

SP - 1362

EP - 1366

JO - Default journal

JF - Default journal

ER -

Visible-light-promoted intramolecular C-H amination in aqueous solution: synthesis of carbazoles

Abstract

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