Flexible ring tire models are widely used for vehicle durability and ride comfort analysis. In our previous research, a novel 3D flexible ring tire model was proposed, and the model’s parameter identification and predictability were illustrated based on various tire cleat tests. To further demonstrate its capability, this paper applies the tire model in a full-vehicle model for various full vehicle bump tests with different driving speeds and cleat orientations in Matlab programing. The tire model and the full-vehicle model are connected through a suspension system, with the suspension spring and damper along the vertical direction, and rigid attachment along the longitudinal and lateral directions. The predicted results are compared against ADAMS® full-vehicle FTire virtual tests with the same simulation conditions. The comparison variables include tire forces, vertical displacements, and suspension jounce movements. The results provide useful guidance for the design of vehicle suspension.