TY - JOUR
T1 - Use of Emotional Cues for Lexical Learning: A Comparison of Autism Spectrum Disorder and Fragile X Syndrome
T2 - A Comparison of Autism Spectrum Disorder and Fragile X Syndrome
AU - Thurman, A.
AU - McDuffie, A.
AU - Kover, S.
AU - Hagerman, R.
AU - Channell, M.
AU - Mastergeorge, Ann
AU - Abbeduto, L.
N1 - Funding Information:
This research was supported by Grant R01 HD054764 from the National Institute of Child Health and Human Development. We wish to thank the children and their families for their participation in this study. We also thank David Benjamin, Susan Harris, Beth Goodlin-Jones, Claire Hauser, Sara Lifson, Eileen Haebig, Ashley Oakes, and Cecilia Compton for assisting with data collection and Susen Schroeder for coordinating all study visits. Leonard Abbeduto has received financial support to develop and implement outcome measures for fragile X syndrome clinical trials from F. Hoffman-LaRoche, Ltd., Roche TCRC, Inc. and Neuren Pharmaceuticals Limited. Randi J. Hagerman has received funding from Novartis, Roche Pharmaceuticals, Curemark, Forest, and Seaside Therapeutics to carry out treatment studies in fragile X syndrome and autism. She has also consulted with Roche/Genetech and Novartis regarding treatment studies in fragile X syndrome. No other authors have financial disclosures to make.
Publisher Copyright:
© 2014, Springer Science+Business Media New York.
PY - 2015/3/20
Y1 - 2015/3/20
N2 - The present study evaluated the ability of males with fragile X syndrome (FXS), nonsyndromic autism spectrum disorder (ASD), or typical development to learn new words by using as a cue to the intended referent an emotional reaction indicating a successful (excitement) or unsuccessful (disappointment) search for a novel object. Performance for all groups exceeded chance-levels in both search conditions. In the Successful Search condition, participants with nonsyndromic ASD performed similarly to participants with FXS after controlling for severity of ASD. In the Unsuccessful Search condition, participants with FXS performed significantly worse than participants with nonsyndromic ASD, after controlling for severity of ASD. Predictors of performance in both search conditions differed between the three groups. Theoretical and clinical implications are discussed.
AB - The present study evaluated the ability of males with fragile X syndrome (FXS), nonsyndromic autism spectrum disorder (ASD), or typical development to learn new words by using as a cue to the intended referent an emotional reaction indicating a successful (excitement) or unsuccessful (disappointment) search for a novel object. Performance for all groups exceeded chance-levels in both search conditions. In the Successful Search condition, participants with nonsyndromic ASD performed similarly to participants with FXS after controlling for severity of ASD. In the Unsuccessful Search condition, participants with FXS performed significantly worse than participants with nonsyndromic ASD, after controlling for severity of ASD. Predictors of performance in both search conditions differed between the three groups. Theoretical and clinical implications are discussed.
KW - Autism spectrum disorder
KW - Emotion
KW - Fast mapping
KW - Fragile X syndrome
KW - Lexical learning
UR - http://www.scopus.com/inward/record.url?scp=84925463449&partnerID=8YFLogxK
U2 - 10.1007/s10803-014-2260-1
DO - 10.1007/s10803-014-2260-1
M3 - Article
C2 - 25318904
VL - 45
SP - 1042
EP - 1061
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 4
ER -