@article{bbf355e334924848a273e298ebafa129,
title = "Tsetse-Wolbachia symbiosis: Comes of age and has great potential for pest and disease control",
abstract = "Tsetse flies (Diptera: Glossinidae) are the sole vectors of African trypanosomes, the causative agent of sleeping sickness in human and nagana in animals. Like most eukaryotic organisms, Glossina species have established symbiotic associations with bacteria. Three main symbiotic bacteria have been found in tsetse flies: Wigglesworthia glossinidia, an obligate symbiotic bacterium, the secondary endosymbiont Sodalis glossinidius and the reproductive symbiont Wolbachia pipientis. In the present review, we discuss recent studies on the detection and characterization of Wolbachia infections in Glossina species, the horizontal transfer of Wolbachia genes to tsetse chromosomes, the ability of this symbiont to induce cytoplasmic incompatibility in Glossina morsitans morsitans and also how new environment-friendly tools for disease control could be developed by harnessing Wolbachia symbiosis.",
keywords = "Glossina, Insect symbiosis, Paratransgenesis, Sodalis, Wigglesworthia, Wolbachia",
author = "Vangelis Doudoumis and Uzma Alam and Emre Aksoy and Abd-Alla, {Adly M.M.} and George Tsiamis and Corey Brelsfoard and Serap Aksoy and Kostas Bourtzis",
note = "Funding Information: We are grateful to FAO/IAEA Coordinated Research Program “Improving SIT for Tsetse Flies through Research on their Symbionts” for the overall support of this study. V.D., G.T., S.A. and K.B. also acknowledge support from EU COST Action FA0701 “Arthropod Symbiosis: From Fundamental Studies to Pest and Disease Management”. This study also received support from the European Community{\textquoteright}s Seventh Framework Programme CSA-SA_REGPROT-2007-1 under Grant Agreement No. 203590 and CSA-SA REGPOT-2008-2 under Grant Agreement 245746 as well as from National Institutes of Health Grants AI06892, D43TW007391, R03TW008413 and Monell Foundation awarded to S.A. G. m. morsitans Whole Genome Sequence is being obtained at the Welcome Trust Sanger Institute, UK under the leadership of The International Glossina Genome Initiative (IGGI) consortium. ",
year = "2013",
month = mar,
doi = "10.1016/j.jip.2012.05.010",
language = "English",
volume = "112",
pages = "S94--S103",
journal = "Journal of Invertebrate Pathology",
issn = "0022-2011",
number = "SUPPL.1",
}