Transition metal- And solvent-free double hydroboration of nitriles

Deepika Bedi; Aneelman Brar; Michael Findlater

doi:10.1039/c9gc04260a

Transition metal- And solvent-free double hydroboration of nitriles

Deepika Bedi, Aneelman Brar, Michael Findlater

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

A highly efficient, room temperature double hydroboration of nitriles under transition metal-free and solvent-free conditions is reported. Sodium triethylborohydride is used as a catalyst and yields up to 99% are disclosed. Mechanistic studies reveal the reaction proceeds in a stepwise manner with initial formation of a boryl-imine which undergoes a second hydroboration to afford a diborylated amine product.

Original language	English
Pages (from-to)	1125-1128
Number of pages	4
Journal	Green Chemistry
Volume	22
Issue number	4
DOIs	https://doi.org/10.1039/c9gc04260a
State	Published - Feb 21 2020

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abstract = "A highly efficient, room temperature double hydroboration of nitriles under transition metal-free and solvent-free conditions is reported. Sodium triethylborohydride is used as a catalyst and yields up to 99% are disclosed. Mechanistic studies reveal the reaction proceeds in a stepwise manner with initial formation of a boryl-imine which undergoes a second hydroboration to afford a diborylated amine product.",

author = "Deepika Bedi and Aneelman Brar and Michael Findlater",

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AU - Brar, Aneelman

AU - Findlater, Michael

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N2 - A highly efficient, room temperature double hydroboration of nitriles under transition metal-free and solvent-free conditions is reported. Sodium triethylborohydride is used as a catalyst and yields up to 99% are disclosed. Mechanistic studies reveal the reaction proceeds in a stepwise manner with initial formation of a boryl-imine which undergoes a second hydroboration to afford a diborylated amine product.

AB - A highly efficient, room temperature double hydroboration of nitriles under transition metal-free and solvent-free conditions is reported. Sodium triethylborohydride is used as a catalyst and yields up to 99% are disclosed. Mechanistic studies reveal the reaction proceeds in a stepwise manner with initial formation of a boryl-imine which undergoes a second hydroboration to afford a diborylated amine product.

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DO - 10.1039/c9gc04260a

M3 - Article

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Transition metal- And solvent-free double hydroboration of nitriles

Abstract

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