Time-restricted feeding plus resistance training in active females: a randomized trial

Grant M. Tinsley, M. Lane Moore, Austin J. Graybeal, Antonio Paoli, Youngdeok Kim, Joaquin Gonzales, John R. Harry, Trisha A. VanDusseldorp, Devin N. Kennedy, Megan Cruz

Research output: Contribution to journalArticlepeer-review


Background: A very limited amount of research has examined intermittent fasting in active populations. Objective: Our objective was to examine the effects of time-restricted feeding (TRF), with or without beta-hydroxy beta-methylbutyrate (HMB) supplementation, during resistance training (RT). Design: This study employed a randomized, placebo-controlled, reduced factorial design and was double-blind with respect to supplementation in TRF groups. Active females were randomized to control diet (CD), TRF or TRF plus 3 g/d HMB (TRFHMB). TRF groups consumed all calories in ~8 h/d. All groups completed 8 weeks of supervised RT and consumed supplemental whey protein. Body composition, muscular performance, dietary intake, physical activity, and physiological variables were assessed. Data were analyzed prior to unblinding using mixed models and both per protocol (PP) and intention-to-treat (ITT) frameworks. Results: Forty participants were included in ITT, while 24 participants were include
Original languageEnglish
Pages (from-to)628-640
JournalAmerican Journal of Clinical Nutrition
StatePublished - Sep 2019


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