TY - JOUR
T1 - Thermo- and pH-responsive fluorescence behaviors of sulfur-functionalized detonation nanodiamond-poly(N-isopropylacrylamide)
AU - Su, Siheng
AU - Wei, Junhua
AU - Zhang, Kun
AU - Qiu, Jingjing
AU - Wang, Shiren
N1 - Publisher Copyright:
© 2015, Springer-Verlag Berlin Heidelberg.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Detonation nanodiamonds (DNDs) are emerging as bioimaging platforms due to their biocompability, small primary particle size, reactive surface, and stable fluorescence after modification. In this paper, a heteroatom engineering method is provided to fabricate the fluorescent DNDs through pyrolysis of dibenzyl disulfide. The quantum yield of these sulfur (S)-functionalized DNDs (SDNDs) increases with sulfur percentage. The solubility and stability of SDNDs in aqueous solution are also significantly increased due to the formation of hydrophilic sulfur groups on DND. Furthermore, these SDNDs are used to conjugate the stimuli-responsive poly(N-isopropylacrylamide) (PNIPAM) through the ‘graft from’ method. The conjugation demonstrated both pH- and thermo-responsive fluorescence behaviors, which shows promise to be used in ratiometric fluorescence sensing for the detection of intracellular pH and temperature values.
AB - Detonation nanodiamonds (DNDs) are emerging as bioimaging platforms due to their biocompability, small primary particle size, reactive surface, and stable fluorescence after modification. In this paper, a heteroatom engineering method is provided to fabricate the fluorescent DNDs through pyrolysis of dibenzyl disulfide. The quantum yield of these sulfur (S)-functionalized DNDs (SDNDs) increases with sulfur percentage. The solubility and stability of SDNDs in aqueous solution are also significantly increased due to the formation of hydrophilic sulfur groups on DND. Furthermore, these SDNDs are used to conjugate the stimuli-responsive poly(N-isopropylacrylamide) (PNIPAM) through the ‘graft from’ method. The conjugation demonstrated both pH- and thermo-responsive fluorescence behaviors, which shows promise to be used in ratiometric fluorescence sensing for the detection of intracellular pH and temperature values.
KW - Nanodiamond
KW - Poly(N-isopropylacrylamide)
KW - Thermo-responsive
KW - pH-responsive
UR - http://www.scopus.com/inward/record.url?scp=84936792792&partnerID=8YFLogxK
U2 - 10.1007/s00396-015-3531-x
DO - 10.1007/s00396-015-3531-x
M3 - Article
AN - SCOPUS:84936792792
SN - 0303-402X
VL - 293
SP - 1299
EP - 1305
JO - Colloid and Polymer Science
JF - Colloid and Polymer Science
IS - 4
ER -