The role of exosomes in breast cancer: What have we learned in ten years?

Belinda M. D’Costa, Naima Moustaid-Moussa, Lauren Gollahon

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

© 2017 Nova Science Publishers, Inc. Although the existence of exosomes has been known for about a decade, it was not until recently that their role as drivers of cancer and their role in restructuring the tumor microenvironment has been demonstrated. Exosomes are extracellular vesicles ranging from 30-100 nanometers in size that have been shown to be produced and released by different cell types. Additionally, exosomes contain material specific to the cell type from which they were released, facilitating backtracking to the tissue of origin. Mounting evidence shows that exosomes play a crucial role in cancer and assist in cell-to-cell communication by transporting nucleic acids and proteins. Intercellular communication between tumor cells and the microenvironment is critical to the growth and progression of the malignant phenotype. This communication can influence the aggressiveness and invasive potential of the cancer. Recent studies have reported that exosomes facilitate tumorigene
Original languageEnglish
Title of host publicationThe role of exosomes in breast cancer: What have we learned in ten years?
Pages1-62
StatePublished - Jan 1 2017

Fingerprint Dive into the research topics of 'The role of exosomes in breast cancer: What have we learned in ten years?'. Together they form a unique fingerprint.

  • Cite this

    D’Costa, B. M., Moustaid-Moussa, N., & Gollahon, L. (2017). The role of exosomes in breast cancer: What have we learned in ten years? In The role of exosomes in breast cancer: What have we learned in ten years? (pp. 1-62)