Weight reduction in overweight and obese individuals results in physiological and behavioral changes that make the prevention of weight regain more difficult than either initial weight loss or the prevention of weight gain. Exercise is recommended for the prevention of weight regain by both governmental agencies and professional organizations. To date, the effectiveness of exercise recommendations for the prevention of weight regain has not been evaluated in a properly designed, adequately powered trial. Therefore, we will conduct a randomized trial to evaluate the effectiveness of 3 levels of exercise on the prevention of weight regain, in initially overweight and obese sedentary men and women. Participants will complete a 3 month weight loss intervention of decreased energy intake (EI) and increased exercise (100 min/week). Participants achieving clinically significant weight loss (≥ 5% of initial weight), will then be randomly assigned to 12 months of verified exercise at 3 levels
|Journal||Contemporary Clinical Trials|
|State||Published - 2013|
Donnelly, J. E., Washburn, R. A., Sullivan, D. K., Honas, J. J., Goetz, J., Mayo, M. S., Lee, J. H., & Szabo, A. N. (2013). The Midwest Exercise Trial for the Prevention of Weight Regain: MET POWeR. Contemporary Clinical Trials, 470–478.