The enantioselective halo aldol reaction utilizing cyclopropyl ketone-derived enolates

Cody Timmons; Guigen Li

doi:10.1016/j.tetlet.2005.07.163

The enantioselective halo aldol reaction utilizing cyclopropyl ketone-derived enolates

Cody Timmons, Guigen Li

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A new enantioselective halo aldol reaction is reported using a chiral borane catalyst. The absolute stereochemistry of the product was unambiguously determined by chemical transformations and a preliminary mechanistic study is reported.

Original language	English
Pages (from-to)	6949-6952
Number of pages	4
Journal	Tetrahedron Letters
Volume	46
Issue number	40
DOIs	https://doi.org/10.1016/j.tetlet.2005.07.163
State	Published - Oct 3 2005

Keywords

Halo aldols
Oxazaborolidine

Access to Document

10.1016/j.tetlet.2005.07.163

Cite this

@article{a94c04947ee247339cf2a173619a3e71,

title = "The enantioselective halo aldol reaction utilizing cyclopropyl ketone-derived enolates",

abstract = "A new enantioselective halo aldol reaction is reported using a chiral borane catalyst. The absolute stereochemistry of the product was unambiguously determined by chemical transformations and a preliminary mechanistic study is reported.",

keywords = "Halo aldols, Oxazaborolidine",

author = "Cody Timmons and Guigen Li",

note = "Funding Information: We gratefully acknowledge the National Institutes of Health (CA 99995-1) and the Robert A. Welch Foundation (D-1361) for the generous support of this work. ",

year = "2005",

month = oct,

day = "3",

doi = "10.1016/j.tetlet.2005.07.163",

language = "English",

volume = "46",

pages = "6949--6952",

journal = "Tetrahedron Letters",

issn = "0040-4039",

number = "40",

}

TY - JOUR

T1 - The enantioselective halo aldol reaction utilizing cyclopropyl ketone-derived enolates

AU - Timmons, Cody

AU - Li, Guigen

N1 - Funding Information: We gratefully acknowledge the National Institutes of Health (CA 99995-1) and the Robert A. Welch Foundation (D-1361) for the generous support of this work.

PY - 2005/10/3

Y1 - 2005/10/3

N2 - A new enantioselective halo aldol reaction is reported using a chiral borane catalyst. The absolute stereochemistry of the product was unambiguously determined by chemical transformations and a preliminary mechanistic study is reported.

AB - A new enantioselective halo aldol reaction is reported using a chiral borane catalyst. The absolute stereochemistry of the product was unambiguously determined by chemical transformations and a preliminary mechanistic study is reported.

KW - Halo aldols

KW - Oxazaborolidine

UR - http://www.scopus.com/inward/record.url?scp=27744494914&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2005.07.163

DO - 10.1016/j.tetlet.2005.07.163

M3 - Article

AN - SCOPUS:27744494914

SN - 0040-4039

VL - 46

SP - 6949

EP - 6952

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 40

ER -

The enantioselective halo aldol reaction utilizing cyclopropyl ketone-derived enolates

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this