The effect of C5 substitution on the photochemistry of uracil

Dana Nachtigallová; Hans Lischka; Jaroslaw J. Szymczak; Mario Barbatti; Pavel Hobza; Zsolt Gengeliczki; Gustavo Pino; Michael P. Callahan; Mattanjah S. De Vries

doi:10.1039/b925803p

The effect of C5 substitution on the photochemistry of uracil

Dana Nachtigallová, Hans Lischka, Jaroslaw J. Szymczak, Mario Barbatti, Pavel Hobza, Zsolt Gengeliczki, Gustavo Pino, Michael P. Callahan, Mattanjah S. De Vries

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

A combined experimental and theoretical study on the excited-state behavior of the uracil analogues, 5-OH-Ura and 5-NH₂-Ura is reported. Two-photon ionization and IR/UV double-resonant spectra show that there is only one tautomer present for each with an excited state lifetime of 1.8 ns for 5-OH-Ura and 12.0 ns for 5-NH₂-Ura as determined from pump-probe experiments. The nature of the excited states of both species is investigated by means of multi-reference ab initio methods. Vertical excitation energies, excited state minima, minima on the crossing seam and reaction paths towards them are determined. Sizeable barriers on these paths are found that provide an explanation for the lifetimes of several nanoseconds observed in the experiment.

Original language	English
Pages (from-to)	4924-4933
Number of pages	10
Journal	Physical Chemistry Chemical Physics
Volume	12
Issue number	19
DOIs	https://doi.org/10.1039/b925803p
State	Published - 2010

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abstract = "A combined experimental and theoretical study on the excited-state behavior of the uracil analogues, 5-OH-Ura and 5-NH2-Ura is reported. Two-photon ionization and IR/UV double-resonant spectra show that there is only one tautomer present for each with an excited state lifetime of 1.8 ns for 5-OH-Ura and 12.0 ns for 5-NH2-Ura as determined from pump-probe experiments. The nature of the excited states of both species is investigated by means of multi-reference ab initio methods. Vertical excitation energies, excited state minima, minima on the crossing seam and reaction paths towards them are determined. Sizeable barriers on these paths are found that provide an explanation for the lifetimes of several nanoseconds observed in the experiment.",

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AU - Nachtigallová, Dana

AU - Lischka, Hans

AU - Szymczak, Jaroslaw J.

AU - Barbatti, Mario

AU - Hobza, Pavel

AU - Gengeliczki, Zsolt

AU - Pino, Gustavo

AU - Callahan, Michael P.

AU - De Vries, Mattanjah S.

PY - 2010

Y1 - 2010

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AB - A combined experimental and theoretical study on the excited-state behavior of the uracil analogues, 5-OH-Ura and 5-NH2-Ura is reported. Two-photon ionization and IR/UV double-resonant spectra show that there is only one tautomer present for each with an excited state lifetime of 1.8 ns for 5-OH-Ura and 12.0 ns for 5-NH2-Ura as determined from pump-probe experiments. The nature of the excited states of both species is investigated by means of multi-reference ab initio methods. Vertical excitation energies, excited state minima, minima on the crossing seam and reaction paths towards them are determined. Sizeable barriers on these paths are found that provide an explanation for the lifetimes of several nanoseconds observed in the experiment.

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The effect of C5 substitution on the photochemistry of uracil

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