The catalytic synthesis of carboniolamide: The role of sp 3 hybridized oxygen

Yi Zhang, Yuchi Dai, Guigen Li, Xu Cheng

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


A catalytic synthesis of carboniolamide has been reported. The strategy was straightforward with aldehyde and amide as starting materials. The products can be isolated as precipitates from the reaction mixture. The factor that stabilizes the labile functionality of hemiaminal was elucidated as a sp 3 hybridized oxygen.

Original languageEnglish
Article numberst-2014-w0612-l
Pages (from-to)2644-2648
Number of pages5
Issue number18
StatePublished - Nov 2014


  • aldehyde
  • amide
  • catalysis
  • nucleophilic addition
  • phosphate


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