The accuracy of ACTH as a biomarker for Pituitary Pars Intermedia Dysfunction in horses: A systematic review and meta-analysis.

Laszlo Hunyadi, James Meyer, Jose Ordonez-Mena

Research output: Contribution to journalArticlepeer-review

Abstract

The objective of the study was to estimate the accuracy and appropriate use of basal ACTH as a diagnostic biomarker of PPID in adult horses and appraise potential causes of study hetergeneity. There is important heterogeneity in the results of studies measuring the diagnostic accuracy of ACTH for PPID. There is a need for less biased studies on the diagnostic accuracy of ACTH. The results suggest that in horses with a high pre-test probability of PPID, ACTH is a useful triage test. The use of ACTH as a screening test or in individuals with a low pre-test probability of PPID is not recommended. <br><br>
Original languageEnglish
JournalEquine Veterinary Journal
StatePublished - Aug 24 2021

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