TY - JOUR
T1 - Teucrium polium Phenylethanol and Iridoid Glycoside Characterization and Flavonoid Inhibition of Biofilm-Forming Staphylococcus aureus
AU - Elmasri, Wael A
AU - Tianjiao, Yang
AU - Tran, Phat
AU - Hegazy, Mohamed-Elamir F
AU - Hamood, Abdul N
AU - Mechref, Yehia
AU - Pare, Paul
PY - 2015/1
Y1 - 2015/1
N2 - The chemical composition and biofilm regulation of 15 metabolites from Teucrium polium are reported. Compounds were isolated from a CH2Cl2−MeOH extract of the aerial parts of the plant and included iridoid and phenylethanol glycosides and a
monoterpenoid, together with nine known compounds. The structures were elucidated based on standard spectroscopic (UV,
1H and 13C NMR), 2D NMR (1H−1H COSY, HMQC, HMBC, and NOESY), and/or LC-ESIMS/MS data analyses. Inhibition of the biofilm-forming strain Staphylococcus aureus was observed with
exposure to compounds 7 and 8.
AB - The chemical composition and biofilm regulation of 15 metabolites from Teucrium polium are reported. Compounds were isolated from a CH2Cl2−MeOH extract of the aerial parts of the plant and included iridoid and phenylethanol glycosides and a
monoterpenoid, together with nine known compounds. The structures were elucidated based on standard spectroscopic (UV,
1H and 13C NMR), 2D NMR (1H−1H COSY, HMQC, HMBC, and NOESY), and/or LC-ESIMS/MS data analyses. Inhibition of the biofilm-forming strain Staphylococcus aureus was observed with
exposure to compounds 7 and 8.
M3 - Article
SP - 2
EP - 9
JO - Journal of Natural Products
JF - Journal of Natural Products
ER -