Teucrium polium Phenylethanol and Iridoid Glycoside Characterization and Flavonoid Inhibition of Biofilm-Forming Staphylococcus aureus

Wael A Elmasri, Yang Tianjiao, Phat Tran, Mohamed-Elamir F Hegazy, Abdul N Hamood, Yehia Mechref, Paul Pare

Research output: Contribution to journalArticle

Abstract

The chemical composition and biofilm regulation of 15 metabolites from Teucrium polium are reported. Compounds were isolated from a CH2Cl2−MeOH extract of the aerial parts of the plant and included iridoid and phenylethanol glycosides and a monoterpenoid, together with nine known compounds. The structures were elucidated based on standard spectroscopic (UV, 1H and 13C NMR), 2D NMR (1H−1H COSY, HMQC, HMBC, and NOESY), and/or LC-ESIMS/MS data analyses. Inhibition of the biofilm-forming strain Staphylococcus aureus was observed with exposure to compounds 7 and 8.
Original languageEnglish
Pages (from-to)2-9
JournalJournal of Natural Products
StatePublished - Jan 2015

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