The chemical composition and bioﬁlm regulation of 15 metabolites from Teucrium polium are reported. Compounds were isolated from a CH2Cl2−MeOH extract of the aerial parts of the plant and included iridoid and phenylethanol glycosides and a monoterpenoid, together with nine known compounds. The structures were elucidated based on standard spectroscopic (UV, 1H and 13C NMR), 2D NMR (1H−1H COSY, HMQC, HMBC, and NOESY), and/or LC-ESIMS/MS data analyses. Inhibition of the bioﬁlm-forming strain Staphylococcus aureus was observed with exposure to compounds 7 and 8.
|Journal||Journal of Natural Products|
|State||Published - Jan 2015|
Elmasri, W. A., Tianjiao, Y., Tran, P., Hegazy, M-E. F., Hamood, A. N., Mechref, Y., & Pare, P. (2015). Teucrium polium Phenylethanol and Iridoid Glycoside Characterization and Flavonoid Inhibition of Biofilm-Forming Staphylococcus aureus. Journal of Natural Products, 2-9.