TY - JOUR
T1 - Teucrium polium phenylethanol and iridoid glycoside characterization and flavonoid inhibition of biofilm-forming staphylococcus aureus
AU - Elmasri, Wael A.
AU - Yang, Tianjiao
AU - Tran, Phat
AU - Hegazy, Mohamed Elamir F.
AU - Hamood, Abdul N.
AU - Mechref, Yehia
AU - Paré, Paul W.
N1 - Publisher Copyright:
© 2014 The American Chemical Society and American Society of Pharmacognosy.
PY - 2015/1/23
Y1 - 2015/1/23
N2 - The chemical composition and biofilm regulation of 15 metabolites from Teucrium polium are reported. Compounds were isolated from a CH2Cl2-MeOH extract of the aerial parts of the plant and included iridoid and phenylethanol glycosides and a monoterpenoid, together with nine known compounds. The structures were elucidated based on standard spectroscopic (UV, 1H and 13C NMR), 2D NMR (1H-1H COSY, HMQC, HMBC, and NOESY), and/or LC-ESIMS/MS data analyses. Inhibition of the biofilm-forming strain Staphylococcus aureus was observed with exposure to compounds 7 and 8.
AB - The chemical composition and biofilm regulation of 15 metabolites from Teucrium polium are reported. Compounds were isolated from a CH2Cl2-MeOH extract of the aerial parts of the plant and included iridoid and phenylethanol glycosides and a monoterpenoid, together with nine known compounds. The structures were elucidated based on standard spectroscopic (UV, 1H and 13C NMR), 2D NMR (1H-1H COSY, HMQC, HMBC, and NOESY), and/or LC-ESIMS/MS data analyses. Inhibition of the biofilm-forming strain Staphylococcus aureus was observed with exposure to compounds 7 and 8.
UR - http://www.scopus.com/inward/record.url?scp=84921661514&partnerID=8YFLogxK
U2 - 10.1021/np5004092
DO - 10.1021/np5004092
M3 - Article
C2 - 25524452
AN - SCOPUS:84921661514
VL - 78
SP - 2
EP - 9
JO - Journal of Natural Products
JF - Journal of Natural Products
SN - 0163-3864
IS - 1
ER -