Temperature effects on high-intensity, ultrashort electric pulse induced cell death

Jiahui Song, Ravindra P. Joshi

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Thermal effect on high-intensity, ultrashort pulses could facilitate poration over small sections of the membrane. It points to the possibility that reduction in the amplitude and pulse shortening for the pulses at increased temperature, can result in pore formation. Molecular Dynamics simulations indicate an increased probability for pore formation in the plasma membrane with lower pulse amplitude or smaller pulse durations at increasing temperatures.

Original languageEnglish
Title of host publicationProceedings - 2014 40th Annual Northeast Bioengineering Conference, NEBEC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781479937288
DOIs
StatePublished - Dec 2 2014
Event2014 40th Annual Northeast Bioengineering Conference, NEBEC 2014 - Boston, United States
Duration: Apr 25 2014Apr 27 2014

Publication series

NameProceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
Volume2014-December
ISSN (Print)1071-121X
ISSN (Electronic)2160-7001

Conference

Conference2014 40th Annual Northeast Bioengineering Conference, NEBEC 2014
CountryUnited States
CityBoston
Period04/25/1404/27/14

Keywords

  • high-intensity
  • molecular dynamics
  • thermal effect
  • ultrashort

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