@article{8c99642b8d674eec9c572aa73e4f0fdd,
title = "Synthesis of 13C7-labeled iodoacetanilide and application to quantitative analysis of peptides and a protein by isotope differential mass spectrometry",
abstract = "13C7-Labeled iodoacetanilide has been synthesized for specific labeling of sulfhydryl groups of cysteine residues and has been successfully applied to quantitative analysis of peptides and a commercial protein in combination with 13C-unlabeled iodoacetanilide and a MALDI mass spectrometer. Subsequent tandem mass spectrum analysis revealed that 13C7-labeled iodoacetanilide remained intact during the collision-induced dissociation (CID) conditions.",
keywords = "Cysteine modifier, Mass spectrometry, Proteomics, Quantitative analysis of peptides",
author = "Satomi Niwayama and Masoud Zabet-Moghaddam and Sadamu Kurono and Hanjoung Cho",
note = "Funding Information: This work is supported by the Texas Tech University-Texas Tech University Health Sciences Center Joint Initiative Grant . We thank the Center for Biotechnology and Genomics, Texas Tech University, for allowing us to use the research facilities. We also thank Ms. Yuka Kaneko of Osaka University Graduate School of Medicine and Wako Pure Chemical Industries, Ltd. for her technical assistance. ",
year = "2009",
month = oct,
day = "1",
doi = "10.1016/j.bmcl.2009.08.011",
language = "English",
volume = "19",
pages = "5698--5702",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
number = "19",
}