TY - JOUR
T1 - Synthesis of d-labeled and unlabeled benzoyloxysuccinimides and application to quantitative analysis of peptides and a protein by isotope differential mass spectrometry
AU - Zabet-Moghaddam, Masoud
AU - Shaikh, Aarif L.
AU - Jones, Lauren B.
AU - Niwayama, Satomi
N1 - Funding Information:
This work is supported by the Texas Tech University-Texas Tech University Health Sciences Center Joint Initiative Grant. We also thank the Center for Biotechnology and Genomics, Texas Tech University for allowing us to use the research facilities.
PY - 2011/8/1
Y1 - 2011/8/1
N2 - Benzoyloxysuccinimide and its d 5-labeled version, which react with amino groups in the N-termini and lysine side chains in proteins, were synthesized and applied to quantitative analysis of peptides and a commercially available protein in combination with a MALDI mass spectrometer.
AB - Benzoyloxysuccinimide and its d 5-labeled version, which react with amino groups in the N-termini and lysine side chains in proteins, were synthesized and applied to quantitative analysis of peptides and a commercially available protein in combination with a MALDI mass spectrometer.
KW - Amino group modifier
KW - Mass spectrometry
KW - Proteomics
KW - Stable isotope-labeling
UR - http://www.scopus.com/inward/record.url?scp=79960352225&partnerID=8YFLogxK
U2 - 10.1016/j.bmcl.2011.05.090
DO - 10.1016/j.bmcl.2011.05.090
M3 - Article
C2 - 21700454
AN - SCOPUS:79960352225
SN - 0960-894X
VL - 21
SP - 4629
EP - 4632
JO - Bioorganic and Medicinal Chemistry Letters
JF - Bioorganic and Medicinal Chemistry Letters
IS - 15
ER -