Synthesis of a soluble ureido-naphthyridine oligomer that self-associates via eight contiguous hydrogen bonds

Michael F. Mayer, Shoji Nakashima, Steven C. Zimmerman

Research output: Contribution to journalArticle

60 Scopus citations

Abstract

(Chemical Equation Presented) An iterative synthetic route to organic-soluble ureido-naphthyridine oligomers has been developed. Use of this protocol allowed synthesis of a short ureido-naphthyridine oligomer, which presents a self-complementary DDAADDAA hydrogen bonding array (D = hydrogen bond donor, A = hydrogen bond acceptor). Strong self-association via eight hydrogen bonds was observed in organic solution.

Original languageEnglish
Pages (from-to)3005-3008
Number of pages4
JournalOrganic Letters
Volume7
Issue number14
DOIs
StatePublished - Jul 7 2005

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