Synergistic Rhodium/Copper Catalysis: Synthesis of 1,3-Enynes and N-Aryl
Enaminones

Nan-Nan Wang; Lei-Rong Huang; Wen-Juan Hao; Tian-Shu Zhang; Guigen Li; Shu-Jiang Tu; Bo Jiang

Synergistic Rhodium/Copper Catalysis: Synthesis of 1,3-Enynes and N-Aryl Enaminones

Nan-Nan Wang, Lei-Rong Huang, Wen-Juan Hao, Tian-Shu Zhang, Guigen Li, Shu-Jiang Tu, Bo Jiang

Chemistry and Biochemistry

Research output: Contribution to journal › Article

Abstract

Synergistic rhodium/copper catalysis enables new three-component coupling reactions of terminal apes and alpha-diazoketones and/or arylamines, allowing dediazotized carbene C-H insertion for the synthesis of functionalized 1,3-enynes and N-aryl enaminones with high stereoselectivity. The synthetic utility of these transformations results in subsequent C-C or/and C-N bond-forming reactions to effectively build up functional molecules with potential significance.

Original language	English
Pages (from-to)	1298-1301
Journal	Organic Letters
State	Published - Mar 2016

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title = "Synergistic Rhodium/Copper Catalysis: Synthesis of 1,3-Enynes and N-Aryl Enaminones",

abstract = "Synergistic rhodium/copper catalysis enables new three-component coupling reactions of terminal apes and alpha-diazoketones and/or arylamines, allowing dediazotized carbene C-H insertion for the synthesis of functionalized 1,3-enynes and N-aryl enaminones with high stereoselectivity. The synthetic utility of these transformations results in subsequent C-C or/and C-N bond-forming reactions to effectively build up functional molecules with potential significance.",

author = "Nan-Nan Wang and Lei-Rong Huang and Wen-Juan Hao and Tian-Shu Zhang and Guigen Li and Shu-Jiang Tu and Bo Jiang",

year = "2016",

month = mar,

language = "English",

pages = "1298--1301",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society (ACS)",

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TY - JOUR

T1 - Synergistic Rhodium/Copper Catalysis: Synthesis of 1,3-Enynes and N-Aryl Enaminones

AU - Wang, Nan-Nan

AU - Huang, Lei-Rong

AU - Hao, Wen-Juan

AU - Zhang, Tian-Shu

AU - Li, Guigen

AU - Tu, Shu-Jiang

AU - Jiang, Bo

PY - 2016/3

Y1 - 2016/3

N2 - Synergistic rhodium/copper catalysis enables new three-component coupling reactions of terminal apes and alpha-diazoketones and/or arylamines, allowing dediazotized carbene C-H insertion for the synthesis of functionalized 1,3-enynes and N-aryl enaminones with high stereoselectivity. The synthetic utility of these transformations results in subsequent C-C or/and C-N bond-forming reactions to effectively build up functional molecules with potential significance.

AB - Synergistic rhodium/copper catalysis enables new three-component coupling reactions of terminal apes and alpha-diazoketones and/or arylamines, allowing dediazotized carbene C-H insertion for the synthesis of functionalized 1,3-enynes and N-aryl enaminones with high stereoselectivity. The synthetic utility of these transformations results in subsequent C-C or/and C-N bond-forming reactions to effectively build up functional molecules with potential significance.

M3 - Article

SP - 1298

EP - 1301

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

ER -