Surface strains in the anterior leaflet of the functioning mitral valve

M. S. Sacks, Z. He, L. Baijens, S. Wanant, P. Shah, H. Sugimoto, A. P. Yoganathan

Research output: Contribution to journalArticlepeer-review

133 Scopus citations


An in vitro approach was developed to quantify both the in-surface strains of the anterior mitral valve (MV) leaflet. Focus was on a ∼4 mmX ∼4 mm region of the center portion of the anterior leaflet by tracking the three-dimensional (3D) motions of 16 surface markers. From the resulting marker motions, the complete in-surface strain tensor was computed, along with the corresponding strain rate information. Relations of the principal strain directions to the underlying collagen fiber architecture were quantified, and the relation to other relevant structural and functional aspects detailed.

Original languageEnglish
Pages (from-to)1281-1290
Number of pages10
JournalAnnals of Biomedical Engineering
Issue number10
StatePublished - 2002


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