Surface modifications of titanium with covalently-bonded silver nanoparticles for antimicrobial applications

Shahrima Maharubin, Xiaomei Shu, Manavi Singh, Benildo De Los Reyes, George Tan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Formation of biofilm on implant surface is one of the majorcauses for port-operative infection. Incorporation ofantimicrobial silver nanoparticles (AgNPs) on implant surfacehas been studied as an effective remedy in recent decades. Thispaper presents a novel AgNPs-titanium composite foilmanufactured through covalent attachment of AgNPs forbiofilm control. This composite foil was fabricated by a seriesof chemical reactions including thiol-derivatization andformation of Ag-S covalent bonds. The film structure andproperties were characterized through scanning electronmicroscopy (SEM), Energy dispersive X-ray Spectroscopy(EDS) and surface profiling. The antimicrobial performancewas examined against gram positive bacterial strainStaphylococcus aureus. Results indicate that the preparedcomposite foil effectively reduced bacterial attachment in shortterm exposure and possess high stability against the release ofnanoparticles. This novel antimicrobial composite material hasa great potential to be used in the future biomedicalinstrumentation.

Original languageEnglish
Title of host publicationAdditive Manufacturing; Manufacturing Equipment and Systems; Bio and Sustainable Manufacturing
PublisherAmerican Society of Mechanical Engineers (ASME)
ISBN (Electronic)9780791858745
DOIs
StatePublished - Jan 1 2019
EventASME 2019 14th International Manufacturing Science and Engineering Conference, MSEC 2019 - Erie, United States
Duration: Jun 10 2019Jun 14 2019

Publication series

NameASME 2019 14th International Manufacturing Science and Engineering Conference, MSEC 2019
Volume1

Conference

ConferenceASME 2019 14th International Manufacturing Science and Engineering Conference, MSEC 2019
CountryUnited States
CityErie
Period06/10/1906/14/19

Keywords

  • Biomedical Manufacturing
  • Composite Film
  • Covalent Attachment
  • Silver Nanoparticles (AgNPs)
  • Titanium Implant

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  • Cite this

    Maharubin, S., Shu, X., Singh, M., De Los Reyes, B., & Tan, G. (2019). Surface modifications of titanium with covalently-bonded silver nanoparticles for antimicrobial applications. In Additive Manufacturing; Manufacturing Equipment and Systems; Bio and Sustainable Manufacturing (ASME 2019 14th International Manufacturing Science and Engineering Conference, MSEC 2019; Vol. 1). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/MSEC2019-2870