TY - JOUR
T1 - Structural properties of organic chemicals as predictors of biodegradation and microbial toxicity in soils
AU - Walton, B. T.
AU - Anderson, T. A.
N1 - Funding Information:
This research was sponsored by the U. S. Environmental Protection Agency, Robert S. Kerr Environmental Research Laboratory,A da, Oklahoma, through InteragencyA greementN umber DW89931473-01-0to the Oak Ridge National Laboratory,w hich is operated by Martin Marietta Energy Systems, Inc., for the U. S. Departmento f Energy under Contract No. DE-AC05-840R21400. PublicationN o. 3111, EnvironmentaSlc iencesD ivision, ORNL.
PY - 1988
Y1 - 1988
N2 - The evaluation of a chemical's persistence in soil is a major source of uncertainty in environmental risk assessments. Structure-activity relationships (SARs) may provide a useful estimation tool for biodegradability and toxicity of chemicals in soils; however, experiments must be designed to minimize or account for competing loss processes. Biodegradation and toxicity SARs have been described for groups of structurally related molecules in soils, but multiple SARs will undoubtedly be required to estimate properties from large data sets that include dissimilar compounds. These studies provide evidence that the SAR approach has applicability to environmental risk assessments for chemicals in soils, despite important limitations to our ability to extrapolate SARs from one homologous series of chemicals to another.
AB - The evaluation of a chemical's persistence in soil is a major source of uncertainty in environmental risk assessments. Structure-activity relationships (SARs) may provide a useful estimation tool for biodegradability and toxicity of chemicals in soils; however, experiments must be designed to minimize or account for competing loss processes. Biodegradation and toxicity SARs have been described for groups of structurally related molecules in soils, but multiple SARs will undoubtedly be required to estimate properties from large data sets that include dissimilar compounds. These studies provide evidence that the SAR approach has applicability to environmental risk assessments for chemicals in soils, despite important limitations to our ability to extrapolate SARs from one homologous series of chemicals to another.
UR - http://www.scopus.com/inward/record.url?scp=0023741569&partnerID=8YFLogxK
U2 - 10.1016/0045-6535(88)90203-2
DO - 10.1016/0045-6535(88)90203-2
M3 - Article
AN - SCOPUS:0023741569
VL - 17
SP - 1501
EP - 1507
JO - Chemosphere
JF - Chemosphere
SN - 0045-6535
IS - 8
ER -