Steroidal Metabolites Transformed by Marchantia polymorpha Cultures Block Breast Cancer Estrogen Biosynthesis

Medicine & Life Sciences

• Marchantia 100%
• Aromatase 61%
• Estrogens 41%
• Androstenedione 34%
• Breast Neoplasms 32%
• MCF-7 Cells 23%
• Cytochrome P-450 Enzyme System 20%
• Biotransformation 16%
• 1,4-androstadiene-3,17-dione 14%
• androstane-3,17-dione 13%
• 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide 12%
• Necrosis 11%
• Tritium 9%
• Acridine Orange 9%
• Ethidium 9%
• Aromatase Inhibitors 8%
• Apoptosis 8%
• Messenger RNA 8%
• Catalytic Domain 6%
• Mass Spectrometry 6%
• Suspensions 6%
• Cultured Cells 6%
• Real-Time Polymerase Chain Reaction 5%
• Adenocarcinoma 5%
• Breast 5%
• Cell Death 5%
• Steroids 5%

Chemistry

• Estrogen 53%
• Biosynthesis 42%
• Metabolite 35%
• Block Like Crystal 33%
• Cytochrome P450 32%
• androst-4-ene-3,17-dione 16%
• Acridine Orange 12%
• Chemical Agent 12%
• Ethidium Bromide 11%
• 1D NMR Spectroscopy 11%
• Tritium 11%
• Cell Death 10%
• Two-Dimensional NMR 10%
• Steroid 9%
• Suspension 7%
• Bromide 7%
• Purification 6%
• Mass Spectrometry 6%