Virgo is designed to detect gravitational waves of both astrophysical and cosmological origin in the frequency range from a few Hz to a few kHz. After the end of the first science run, partially overlapped with the LIGO fifth science run, the detector underwent several upgrades to improve its sensitivity. The second Virgo science run started at the beginning of July 2009 in coincidence with LIGO. A further upgrade is planned at beginning of 2010 with the installation of new suspensions for the test masses and of new mirrors. This will lead to a considerable improvement in the sensitivity and represents an intermediate step toward the development of the advanced detectors.