Size-dependent antibacterial behavior of graphene quantum dots

Siheng Su, Carla B. Shelton, Jingjing Qiu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Scopus citations

Abstract

In this study, the antibacterial behavior of differing sized graphene quantum dots (GQDs) was studied. The gram negative bacteria, Escherichia coli (E. coli), were used as the bacteria mode. Different sized GQDs with tunable fluorescent colors were acquired by a gel-filtration method. The size, surface chemistry, and photoluminescence properties of GQDs were characterized, respectively. The viability of GQDs treated bacteria was determined by the standard plate counting method. Moreover, the reactive oxidative species (ROS) level was detected by the 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) method. The integrality of the bacteria membrane was observed under the scanning electron microscopy (SEM). The experimental results indicated that GQDs demonstrated size-dependent and surface chemistry-dependent antibacterial behaviors. This research provided insightful guidelines in the selection of suitable GQDs for their potential bioapplications.

Original languageEnglish
Title of host publicationSafety, Reliability and Risk; Virtual Podium (Posters)
PublisherAmerican Society of Mechanical Engineers (ASME)
ISBN (Print)9780791856444
DOIs
StatePublished - 2013
EventASME 2013 International Mechanical Engineering Congress and Exposition, IMECE 2013 - San Diego, CA, United States
Duration: Nov 15 2013Nov 21 2013

Publication series

NameASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
Volume15

Conference

ConferenceASME 2013 International Mechanical Engineering Congress and Exposition, IMECE 2013
Country/TerritoryUnited States
CitySan Diego, CA
Period11/15/1311/21/13

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