Silver-Promoted Site-Selective Intramolecular Cyclization of 2-Methylthiobenzamide through α-C(sp3)-H Functionalization

Ke Yang, Ben Niu, Zhiyan Ma, Hui Wang, Brianna Lawrence, Haibo Ge

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Silver-mediated intramolecular α-C(sp3)-H bond functionalization of the methylthio group has been established in the presence of Selectfluor as an additive. This novel strategy provides efficient access to various diverse sulfur-based heterocycles with good yields and functional group compatibility. It is noteworthy that the completely novel benzooxathiin-4-imine skeletons were reported for the first time in this study.

Original languageEnglish
Pages (from-to)14045-14052
Number of pages8
JournalJournal of Organic Chemistry
Volume84
Issue number21
DOIs
StatePublished - Nov 1 2019

Fingerprint Dive into the research topics of 'Silver-Promoted Site-Selective Intramolecular Cyclization of 2-Methylthiobenzamide through α-C(sp<sup>3</sup>)-H Functionalization'. Together they form a unique fingerprint.

Cite this