Abstract
Need some direction? Silanol was developed as a directing group for the Pd II-catalyzed oxidative Heck-type reaction of arenes. A one-pot C-H activation/desilylation process of benzyldiisopropylsilanol was also demonstrated, providing a powerful approach for the synthesis of ortho-alkenyl-substituted alkylarenes (see scheme). Considering the easily attachable and readily removable properties of the silanol group, this reaction will find broad synthetic applications.
Original language | English |
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Pages (from-to) | 14371-14374 |
Number of pages | 4 |
Journal | Chemistry - A European Journal |
Volume | 17 |
Issue number | 51 |
DOIs | |
State | Published - Dec 16 2011 |
Keywords
- arenes
- directing groups
- olefination
- palladium
- silanols