Silanol as a removable directing group for the pd II-catalyzed direct olefination of arenes

Cong Wang, Haibo Ge

Research output: Contribution to journalArticle

73 Scopus citations

Abstract

Need some direction? Silanol was developed as a directing group for the Pd II-catalyzed oxidative Heck-type reaction of arenes. A one-pot C-H activation/desilylation process of benzyldiisopropylsilanol was also demonstrated, providing a powerful approach for the synthesis of ortho-alkenyl-substituted alkylarenes (see scheme). Considering the easily attachable and readily removable properties of the silanol group, this reaction will find broad synthetic applications.

Original languageEnglish
Pages (from-to)14371-14374
Number of pages4
JournalChemistry - A European Journal
Volume17
Issue number51
DOIs
StatePublished - Dec 16 2011

Keywords

  • arenes
  • directing groups
  • olefination
  • palladium
  • silanols

Fingerprint Dive into the research topics of 'Silanol as a removable directing group for the pd <sup>II</sup>-catalyzed direct olefination of arenes'. Together they form a unique fingerprint.

  • Cite this