TY - JOUR
T1 - Sex-dependent associations between daily physical activity and leg exercise blood pressure responses
AU - Gonzales, Joaquin U.
AU - Grinnell, Dustin M.
AU - Kalasky, Martha J.
AU - Proctor, David N.
PY - 2011/10
Y1 - 2011/10
N2 - The authors examined interindividual and sex-specific variation in systolic (SBP) and diastolic (DBP) blood pressure responses to graded leg-extension exercise in healthy older (60-78 yr) women (n = 21) and men (n = 19). Maximal oxygen uptake (VO2max), body composition, physical activity (accelerometry), and vascular function were measured to identify predictors of exercise BP. Neither VO2max nor activity counts were associated with the rise in SBP or DBP during exercise in men. The strongest predictors of these responses in men were age (SBP: r2 =.19, p =.05) and peak exercise leg vasodilation (DBP: r2 = -.21, p <.05). In women, the modest relationship observed between VO2max and exercise BP was abolished after adjusting for central adiposity and activity counts (best predictors, cumulative r2 =.53, p <.05, for both SBP and DBP). These results suggest that determinants of variation in submaximal exercise BP responses among older adults are sex specific, with daily physical activity influencing these responses in women but not men.
AB - The authors examined interindividual and sex-specific variation in systolic (SBP) and diastolic (DBP) blood pressure responses to graded leg-extension exercise in healthy older (60-78 yr) women (n = 21) and men (n = 19). Maximal oxygen uptake (VO2max), body composition, physical activity (accelerometry), and vascular function were measured to identify predictors of exercise BP. Neither VO2max nor activity counts were associated with the rise in SBP or DBP during exercise in men. The strongest predictors of these responses in men were age (SBP: r2 =.19, p =.05) and peak exercise leg vasodilation (DBP: r2 = -.21, p <.05). In women, the modest relationship observed between VO2max and exercise BP was abolished after adjusting for central adiposity and activity counts (best predictors, cumulative r2 =.53, p <.05, for both SBP and DBP). These results suggest that determinants of variation in submaximal exercise BP responses among older adults are sex specific, with daily physical activity influencing these responses in women but not men.
KW - Accelerometer
KW - Adiposity
KW - Aging
KW - Cardiorespiratory fitness
KW - Gender differences
UR - http://www.scopus.com/inward/record.url?scp=80054726994&partnerID=8YFLogxK
U2 - 10.1123/japa.19.4.306
DO - 10.1123/japa.19.4.306
M3 - Article
C2 - 21911873
AN - SCOPUS:80054726994
SN - 1063-8652
VL - 19
SP - 306
EP - 321
JO - Journal of Aging and Physical Activity
JF - Journal of Aging and Physical Activity
IS - 4
ER -