TY - JOUR
T1 - Self-consistent simulations of electroporation dynamics in biological cells subjected to ultrashort electrical pulses
AU - Joshi, R. P.
AU - Hu, Q.
AU - Aly, R.
AU - Schoenbach, K. H.
AU - Hjalmarson, H. P.
PY - 2001/7
Y1 - 2001/7
N2 - A self-consistent model analysis of electroporation in biological cells was carried out based on the coupled Laplace-Nernst-Planck-Smoluchowski equations. The physical processes of pore generation, drift, and diffusion in r space were all comprehensively included. A pore-radius-dependent energy barrier to ionic transport accounted for cellular variations. As a result, predictions and qualitative understanding of the cellular response to short, high electric field pulses were obtained.
AB - A self-consistent model analysis of electroporation in biological cells was carried out based on the coupled Laplace-Nernst-Planck-Smoluchowski equations. The physical processes of pore generation, drift, and diffusion in r space were all comprehensively included. A pore-radius-dependent energy barrier to ionic transport accounted for cellular variations. As a result, predictions and qualitative understanding of the cellular response to short, high electric field pulses were obtained.
UR - http://www.scopus.com/inward/record.url?scp=84983698520&partnerID=8YFLogxK
U2 - 10.1103/PhysRevE.64.011913
DO - 10.1103/PhysRevE.64.011913
M3 - Article
AN - SCOPUS:84983698520
SN - 1539-3755
VL - 64
SP - 1
EP - 10
JO - Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
JF - Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
IS - 1
M1 - 011913
ER -