Selenium coated contact lenses: Effect upon corneal epithelial cells and bacterial biofilm attachment

T. W. Reid, S. M. Mathews, M. J. Grimson, J. E. Spallholz

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The safety and effectiveness of a covalent organo-selenium coating on silicone hydrogel contact lenses were investigated. It was observed that selenium compounds interacting with thiols in the tear film can catalyze the formation of superoxide radicals. Epithelial and full thickness corneal pachymetry was measured pre- and post-wear and contact lenses were examined chamically for protein and lipid deposition. It was found that the selenium-coated lenses had no adverse effects on the corneas of New Zealand albino rabbits as seen by pachymetry, histology, SEM, and slit lamp examination.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages1610
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Conference

ConferenceTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period05/17/0405/21/04

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