The trace element selenium (Se) is an essential nutrient, but is toxic when consumed in excessive quantities. Selenosis or selenium toxicity signs in animals were described by Marco Polo in 1295 during his travels to China. It was 1934 before Franke 1 identified Se as a toxic agent found in some plant foods. About 20 years later, Schwarz and Foltz 2 demonstrated that, for the rat, Se was an essential dietary element that prevented liver necrosis. Subsequently, Se deficiency syndromes have been identified in animals and humans. Cardiomyopathy, muscle pain and osteoarthropathy are key features of Se deficiency in humans. 3.
|Title of host publication||Sports Nutrition|
|Subtitle of host publication||Vitamins and Trace Elements, Second Edition|
|Number of pages||12|
|ISBN (Print)||084933022X, 9780849330223|
|State||Published - Jan 1 2005|