L. Mallory Boylan, Julian E. Spallholz

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations


The trace element selenium (Se) is an essential nutrient, but is toxic when consumed in excessive quantities. Selenosis or selenium toxicity signs in animals were described by Marco Polo in 1295 during his travels to China. It was 1934 before Franke 1 identified Se as a toxic agent found in some plant foods. About 20 years later, Schwarz and Foltz 2 demonstrated that, for the rat, Se was an essential dietary element that prevented liver necrosis. Subsequently, Se deficiency syndromes have been identified in animals and humans. Cardiomyopathy, muscle pain and osteoarthropathy are key features of Se deficiency in humans. 3.

Original languageEnglish
Title of host publicationSports Nutrition
Subtitle of host publicationVitamins and Trace Elements, Second Edition
PublisherCRC Press
Number of pages12
ISBN (Electronic)9781420037913
ISBN (Print)084933022X, 9780849330223
StatePublished - Jan 1 2005


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