Sarcoehrenbergilides D-F: Cytotoxic cembrene diterpenoids from the soft coral: Sarcophyton ehrenbergi

Mohamed Elamir Hegazy, Tarik A. Mohamed, Abdelsamed I. Elshamy, Ahmed R. Hamed, Mahmoud A.A. Ibrahim, Shinji Ohta, Akemi Umeyama, Paul Pare, Thomas Efferth

Research output: Contribution to journalArticlepeer-review

Abstract

A solvent extract of the soft coral Sarcophyton ehrenbergi afforded cembrene diterpenoids, sarcoehrenbergilid D–F (1–3). Chemical structures were established by modern spectroscopic techniques with absolute stereochemistries determined by circular dichroism (CD) and time-dependent density functional theory electronic CD calculations (TDDFT-ECD). Cytotoxicity activities for 1–3 were evaluated against three human cancer cell lines: lung (A549), colon (Caco-2) and liver (HepG2).
Original languageEnglish
Pages (from-to)27183-27189
JournalDefault journal
StatePublished - Jan 1 2019

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