Sarcoehrenbergilides D-F: Cytotoxic cembrene diterpenoids from the soft coral: Sarcophyton ehrenbergi

Mohamed Elamir F. Hegazy, Tarik A. Mohamed, Abdelsamed I. Elshamy, Ahmed R. Hamed, Mahmoud A.A. Ibrahim, Shinji Ohta, Akemi Umeyama, Paul W. Paré, Thomas Efferth

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

A solvent extract of the soft coral Sarcophyton ehrenbergi afforded cembrene diterpenoids, sarcoehrenbergilid D-F (1-3). Chemical structures were established by modern spectroscopic techniques with absolute stereochemistries determined by circular dichroism (CD) and time-dependent density functional theory electronic CD calculations (TDDFT-ECD). Cytotoxicity activities for 1-3 were evaluated against three human cancer cell lines: lung (A549), colon (Caco-2) and liver (HepG2).

Original languageEnglish
Pages (from-to)27183-27189
Number of pages7
JournalRSC Advances
Volume9
Issue number47
DOIs
StatePublished - 2019

Fingerprint Dive into the research topics of 'Sarcoehrenbergilides D-F: Cytotoxic cembrene diterpenoids from the soft coral: Sarcophyton ehrenbergi'. Together they form a unique fingerprint.

Cite this