TY - JOUR
T1 - Response to ractopamine-HCl in heifers is altered by implant strategy across days on feed
AU - Sissom, E. K.
AU - Reinhardt, C. D.
AU - Hutcheson, J. P.
AU - Nichols, W. T.
AU - Yates, D. A.
AU - Swingle, R. S.
AU - Johnson, B. J.
PY - 2007/9
Y1 - 2007/9
N2 - Two experiments were conducted to investigate the effects of ractopamine-HCl (RAC) and implant strategy or days on feed (DOF) on feedlot performance and expression of β-adrenergic receptors (AR). In Exp. 1, 1,147 feedlot heifers weighing 282 ±3 kg were used with implant treatments of Revalor-200 (R200) at arrival, or Revalor-IH at arrival with reimplantation with Finaplix-H on d 58 (RF). Ractopamine (0 vs. 200 mg/d) was fed the last 28 d in both experiments. Treatments were randomly assigned to 16 pens. At slaughter, semimembranosus muscle tissue was excised for RNA isolation. Ractopamine administration increased (P < 0.05) ADG, G:F, HCW, and LM; decreased (P < 0.05) 12th rib fat depth; and improved (P < 0.05) yield grade. There was no effect (P > 0.10) on the expression of β1 AR mRNA; however, there was a tendency (P = 0.10) for RAC feeding to increase β-AR mRNA levels. For β3-AR mRNA, there was an implant by RAC interaction (P = 0.05), with RAC numerically increasing β3-AR mRNA in heifers implanted with RF, but a decrease (P < 0.05) in expression in heifers implanted with R200. Ractopamine also decreased (P < 0.05) IGF-I mRNA in heifers implanted with RF. In Exp. 2, 2,077 heifers were used to investigate the effects of RAC and DOF. Days on feed were 129, 150, and 170, and RAC was administered the last 28 d. Ractopamine improved (P < 0.05) G:F, but had no other effects (P > 0.05) on performance. Average daily gain decreased (P < 0.05) as DOF increased. Hot carcass weight, LM area, 12th rib fat, G:F, calculated yield grade, and marbling score increased (P < 0.05) and the percentage of KPH fat decreased (P < 0.05) as DOF increased. These data aid in our understanding of the effects of steroidal implants, DOF, and RAC administration in feedlot heifers.
AB - Two experiments were conducted to investigate the effects of ractopamine-HCl (RAC) and implant strategy or days on feed (DOF) on feedlot performance and expression of β-adrenergic receptors (AR). In Exp. 1, 1,147 feedlot heifers weighing 282 ±3 kg were used with implant treatments of Revalor-200 (R200) at arrival, or Revalor-IH at arrival with reimplantation with Finaplix-H on d 58 (RF). Ractopamine (0 vs. 200 mg/d) was fed the last 28 d in both experiments. Treatments were randomly assigned to 16 pens. At slaughter, semimembranosus muscle tissue was excised for RNA isolation. Ractopamine administration increased (P < 0.05) ADG, G:F, HCW, and LM; decreased (P < 0.05) 12th rib fat depth; and improved (P < 0.05) yield grade. There was no effect (P > 0.10) on the expression of β1 AR mRNA; however, there was a tendency (P = 0.10) for RAC feeding to increase β-AR mRNA levels. For β3-AR mRNA, there was an implant by RAC interaction (P = 0.05), with RAC numerically increasing β3-AR mRNA in heifers implanted with RF, but a decrease (P < 0.05) in expression in heifers implanted with R200. Ractopamine also decreased (P < 0.05) IGF-I mRNA in heifers implanted with RF. In Exp. 2, 2,077 heifers were used to investigate the effects of RAC and DOF. Days on feed were 129, 150, and 170, and RAC was administered the last 28 d. Ractopamine improved (P < 0.05) G:F, but had no other effects (P > 0.05) on performance. Average daily gain decreased (P < 0.05) as DOF increased. Hot carcass weight, LM area, 12th rib fat, G:F, calculated yield grade, and marbling score increased (P < 0.05) and the percentage of KPH fat decreased (P < 0.05) as DOF increased. These data aid in our understanding of the effects of steroidal implants, DOF, and RAC administration in feedlot heifers.
KW - Bovine
KW - Heifer
KW - Ractopamine
KW - Skeletal muscle
KW - Steroidal implant
UR - http://www.scopus.com/inward/record.url?scp=34548348311&partnerID=8YFLogxK
U2 - 10.2527/jas.2006-660
DO - 10.2527/jas.2006-660
M3 - Article
C2 - 17504961
AN - SCOPUS:34548348311
SN - 0021-8812
VL - 85
SP - 2125
EP - 2132
JO - Journal of animal science
JF - Journal of animal science
IS - 9
ER -