TY - JOUR
T1 - Research of mitral valve model in the OD left ventricular circulation system
AU - Zhang, Guijie
AU - Wang, Hao
AU - Jing, Teng
AU - He, Zhaoming
PY - 2017/6/20
Y1 - 2017/6/20
N2 - This study presented a leaflet motion resistance model of the mitral valve that could simulate the mitral valve dynamics accurately. This model had a variable resistance based on mitral valve leaflet opening angle 0 and involved the dynamic control equation of the mitral valve movement and main factors affecting the movement of the leaflets: transvalvular pressure and the blood flow force when it applied in the 0 - D lumped parameter model of left heart circulation system, the hemodynamics were derived. The results of this model and step-function with instant valve closure and empirically specified time-varying resistance models were compared under the same cardiac output and regurgitation in left ventricular blood circulation. The leaflet motion resistance model reflected the hemodynamics of the closing process, including the delayed blood flow behind pressure and closing volume. In addition, the model allowed adjustment of the time required for valve opening and closing by changing the impact coefficients of moment of inertial of the leaflet, transvalvular pressure and blood flow-rate, the time of valve opening and closing were 50. 0 ms and 40. 2 ms. The model eliminated the shortcomings of ignoring leaflet motion of the step-function resistance model and avoided the irrational starting time of valve closing of the time-varying resistance model. The model simulated the mitral valve dynamics accurately and was easy to control.
AB - This study presented a leaflet motion resistance model of the mitral valve that could simulate the mitral valve dynamics accurately. This model had a variable resistance based on mitral valve leaflet opening angle 0 and involved the dynamic control equation of the mitral valve movement and main factors affecting the movement of the leaflets: transvalvular pressure and the blood flow force when it applied in the 0 - D lumped parameter model of left heart circulation system, the hemodynamics were derived. The results of this model and step-function with instant valve closure and empirically specified time-varying resistance models were compared under the same cardiac output and regurgitation in left ventricular blood circulation. The leaflet motion resistance model reflected the hemodynamics of the closing process, including the delayed blood flow behind pressure and closing volume. In addition, the model allowed adjustment of the time required for valve opening and closing by changing the impact coefficients of moment of inertial of the leaflet, transvalvular pressure and blood flow-rate, the time of valve opening and closing were 50. 0 ms and 40. 2 ms. The model eliminated the shortcomings of ignoring leaflet motion of the step-function resistance model and avoided the irrational starting time of valve closing of the time-varying resistance model. The model simulated the mitral valve dynamics accurately and was easy to control.
KW - Heart valve dynamics
KW - Leaflet motion resistance model
KW - Left ventricular circulation system
KW - Valve closing process
UR - http://www.scopus.com/inward/record.url?scp=85024472962&partnerID=8YFLogxK
U2 - 10.3969/j.issn.0258-8021.2017.03.006
DO - 10.3969/j.issn.0258-8021.2017.03.006
M3 - Article
AN - SCOPUS:85024472962
VL - 36
SP - 300
EP - 307
JO - Chinese Journal of Biomedical Engineering
JF - Chinese Journal of Biomedical Engineering
SN - 0258-8021
IS - 3
ER -