Relation of femoral diameter, shear rate, and dilatory response to knee extensor exercise

Joaquin Gonzales, Julie A. Midelar, Beth A. Parker, David N. Proctor

Research output: Contribution to journalArticlepeer-review


INTRODUCTION: Younger women typically exhibit marked dilation of the common femoral artery (CFA) during knee extensor exercise; this is in apparent contrast to subject groups with larger (men) and/or older (older women) vessels, which on average display much smaller exerciseinduced increases in CFA diameter. To gain additional insight into this variation, the present study closely examined within- and between-group relationships between CFA diameter, shear rate, and the magnitude of exercise-induced CFA dilation. METHODS: Healthy women (15 younger, 18 older) and men (15 younger, 13 older) performed graded single-leg knee extensor exercise while CFA diameter and blood velocity were measured using Doppler ultrasound. RESULTS: Resting CFA diameter was smaller (P < 0.05) in women (younger: 0.71 +/- 0.02 cm; older: 0.72 +/- 0.02 cm) as compared to men (younger: 0.84 +/- 0.01 cm; older: 0.97 +/- 0.03 cm). Resting CFA diameter was inversely associated with peak shear rate (combined groups,
Original languageEnglish
Pages (from-to)1875-1875
JournalMedicine & Science in Sports & Exercise
StatePublished - Oct 20 2010


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