Abstract
(Chemical Equation Presented) Coumarin and flavone derivatives are highly valuable molecules in drug discovery. Here, two new regioselective cross-dehydrogenation couplings of coumarins and flavones with different ethers via C(sp3)-H functionalization processes were developed, generating new ether-substituted derivatives not previously reported. These reactions proceeded well via radical mechanisms and provided the corresponding products in good yields.
Original language | English |
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Pages (from-to) | 7251-7257 |
Number of pages | 7 |
Journal | Journal of Organic Chemistry |
Volume | 80 |
Issue number | 14 |
DOIs | |
State | Published - Jul 17 2015 |