Regioselective aminohalogenation of β-nitrostyrenes using NCS and NBS as nitrogen/halogen sources

Sanjun Zhi, Hao Sun, Chen Lin, Guangqian Zhang, Guigen Li, Yi Pan

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Aminohalogenation reaction of β-nitrostyrenes with N-halosuccinimides (N-chloro and N-bromosuccinimides) has been successfully conducted by using nickel acetate as a catalyst in the presence of potassium carbonate and succinimide as co-additives. The reaction was easily performed at room temperature under nitrogen gas protection to give dihalorinaed haloamino products in good to excellent yields (60%-98%). The structure has been confirmed by X-ray crystal structure analysis.

Original languageEnglish
Pages (from-to)140-146
Number of pages7
JournalScience China Chemistry
Volume53
Issue number1
DOIs
StatePublished - Jan 2010

Keywords

  • Aminohalogenation
  • NBS
  • NCS
  • Vicinal haloamines
  • β-nitrostyrenes

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