Rapid data analysis method for differential mobility cytometry

Randall D. Reif, Kelong Wang, Dimitri Pappas

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Differential mobility cytometry (DMC) has recently been established as a powerful method to capture cells and study adhesion processes. DMC uses an oscillation system and cell affinity chromatography to monitor cells as they adhere to a surface. In the past, differential images had to be created individually which limited the throughput of the method. A new method to create differential images is presented. The method involves the subtraction of short movies from each other to create a stack of differential images that can be easily analyzed. In the future, this method will make DMC more accessible and improve throughput.

Original languageEnglish
Pages (from-to)2411-2413
Number of pages3
JournalAnalytical and Bioanalytical Chemistry
Volume395
Issue number7
DOIs
StatePublished - Dec 2009

Keywords

  • Cell adhesion
  • Cell affinity chromatography
  • Differential mobility cytometry

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