TY - JOUR
T1 - Queueing models of potentially lethal damage repair in irradiated cells
AU - Myasnikova, Ekaterina M.
AU - Rachev, Svetlozar T.
AU - Yakovlev, Andrej Yu
PY - 1996/7/1
Y1 - 1996/7/1
N2 - Some of the ideas arising in queueing theory are applied to describe the repair mechanisms responsible for recovery of cells from potentially lethal radiation damage. Two alternative versions are presented of a queueing model of damage repair after a single dose of irradiation. The first version represents a linear misrepair model, and the second invokes the idea of spontaneous lesion fixation. They are pieced together in the third model, allowing for both mechanisms. The consistency of the proposed models with published experimental data is tested.
AB - Some of the ideas arising in queueing theory are applied to describe the repair mechanisms responsible for recovery of cells from potentially lethal radiation damage. Two alternative versions are presented of a queueing model of damage repair after a single dose of irradiation. The first version represents a linear misrepair model, and the second invokes the idea of spontaneous lesion fixation. They are pieced together in the third model, allowing for both mechanisms. The consistency of the proposed models with published experimental data is tested.
UR - http://www.scopus.com/inward/record.url?scp=0029904413&partnerID=8YFLogxK
U2 - 10.1016/0025-5564(95)00173-5
DO - 10.1016/0025-5564(95)00173-5
M3 - Article
C2 - 8688567
AN - SCOPUS:0029904413
VL - 135
SP - 85
EP - 109
JO - Mathematical Biosciences
JF - Mathematical Biosciences
SN - 0025-5564
IS - 1
ER -