Queueing models of potentially lethal damage repair in irradiated cells

Ekaterina M. Myasnikova, Svetlozar T. Rachev, Andrej Yu Yakovlev

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Some of the ideas arising in queueing theory are applied to describe the repair mechanisms responsible for recovery of cells from potentially lethal radiation damage. Two alternative versions are presented of a queueing model of damage repair after a single dose of irradiation. The first version represents a linear misrepair model, and the second invokes the idea of spontaneous lesion fixation. They are pieced together in the third model, allowing for both mechanisms. The consistency of the proposed models with published experimental data is tested.

Original languageEnglish
Pages (from-to)85-109
Number of pages25
JournalMathematical Biosciences
Volume135
Issue number1
DOIs
StatePublished - Jul 1 1996

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