PSXV-27 Late-Breaking: Evaluation of antioxidant capacity in receiving beef calves challenged with lipopolysaccharide (LPS)

Samantha N Barker, Treylr Jackson, John Richeson, Jeff A Carroll, Nicole C Burdick-Sanchez, Paul R Broadway, Jerrad Legako

Research output: Other contributionpeer-review

Abstract

<jats:title>Abstract</jats:title><br> <jats:p>The objective of this study was to evaluate antioxidant capacity in plasma of beef calves challenged with LPS. Following an initial feeding period of 40 d, steers (n = 32; 379 kg ± 30.7) were transported to the Livestock Issues Research Unit’s Bovine Immunology Research and Development Complex and challenged intravenously with LPS (0.25 µg/kg BW) on d 41. Blood samples were collected via jugular catheter at -2, 0, 2, 4, 6, 8, 10, 12, 18, 24, 36 and 48 h relative to the LPS challenge at 0 h. Blood samples were processed to isolate plasma for indicators of oxidative stress with a colorimetric assay to determine ferric reducing antioxidant power (FRAP) values via concentration of ferrous iron (µM). Data were analyzed as repeated measures using the GLIMMIX procedure of SAS. Antioxidant values did vary with time (P &amp;lt; 0.001) being greater (P &amp;lt; 0.05) at -2, 0, 2, 36, and 48 h. Antioxidant capacity was reduced at 6 and
Original languageEnglish
PublisherOxford University Press (OUP)
Volume99
DOIs
StatePublished - Oct 8 2021

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