TY - JOUR
T1 - Protein-, polymer-, and silica-based luminescent nanomaterial probes for super resolution microscopy
T2 - a review
AU - Thompson, S.
AU - Pappas, Dimitri
N1 - Funding Information:
ST and DP would like to acknowledge support from the National Institutes of Health (GM 120669) and National Science Foundation (1849063).
Publisher Copyright:
© The Royal Society of Chemistry 2021.
PY - 2021/4/7
Y1 - 2021/4/7
N2 - Super resolution microscopy was developed to overcome the Abbe diffraction limit, which effects conventional optical microscopy, in order to study the smaller components of biological systems. In recent years nanomaterials have been explored as luminescent probes for super resolution microscopy, as many have advantages over traditional fluorescent dye molecules. This review will summarize several different types of nanomaterial probes, covering quantum dots, carbon dots, and dye doped nanoparticles. For the purposes of this review the term “nanoparticle” will be limited to polymer-based, protein-based, and silica-based nanoparticles, including core-shell structured nanoparticles. Luminescent nanomaterials have shown promise as super-resolution probes, and continued research in this area will yield new advances in both materials science and biochemical microscopy at the nanometer scale.
AB - Super resolution microscopy was developed to overcome the Abbe diffraction limit, which effects conventional optical microscopy, in order to study the smaller components of biological systems. In recent years nanomaterials have been explored as luminescent probes for super resolution microscopy, as many have advantages over traditional fluorescent dye molecules. This review will summarize several different types of nanomaterial probes, covering quantum dots, carbon dots, and dye doped nanoparticles. For the purposes of this review the term “nanoparticle” will be limited to polymer-based, protein-based, and silica-based nanoparticles, including core-shell structured nanoparticles. Luminescent nanomaterials have shown promise as super-resolution probes, and continued research in this area will yield new advances in both materials science and biochemical microscopy at the nanometer scale.
UR - http://www.scopus.com/inward/record.url?scp=85103742424&partnerID=8YFLogxK
U2 - 10.1039/d0na00971g
DO - 10.1039/d0na00971g
M3 - Review article
AN - SCOPUS:85103742424
VL - 3
SP - 1853
EP - 1864
JO - Nanoscale Advances
JF - Nanoscale Advances
SN - 2516-0230
IS - 7
ER -