Proposal to present #12e: A proteomic approach to identify physiological changes in e. coli metabolically engineered for enhanced tce degradation and toxicity reduction

C. M.R. Lacerda, K. F. Reardon, L. Rui, T. K. Wood

Research output: Contribution to conferencePaperpeer-review

Abstract

A proteomic approach proposed for identifying the changes in E.coli, metabolically engineered for improved degradation of trichloroethylene (TCE) was investigated. In the metabolic engineering approach to improve aerobic biodegradation, toluene ortho-monoxygenase (TOM)-Green, glutathione S-transferase (GST) and GSHI were co-expressed in E.coli. The genetic manipulations resulted in a variety of physiological changes in the bacterial cells. These changes were found to improve the performance of these microorganisms to degrade pollutants and toxics.

Original languageEnglish
Pages1913-1914
Number of pages2
StatePublished - 2004
Event2004 AIChE Annual Meeting - Austin, TX, United States
Duration: Nov 7 2004Nov 12 2004

Conference

Conference2004 AIChE Annual Meeting
CountryUnited States
CityAustin, TX
Period11/7/0411/12/04

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