A proteomic approach proposed for identifying the changes in E.coli, metabolically engineered for improved degradation of trichloroethylene (TCE) was investigated. In the metabolic engineering approach to improve aerobic biodegradation, toluene ortho-monoxygenase (TOM)-Green, glutathione S-transferase (GST) and GSHI were co-expressed in E.coli. The genetic manipulations resulted in a variety of physiological changes in the bacterial cells. These changes were found to improve the performance of these microorganisms to degrade pollutants and toxics.
|Number of pages||2|
|State||Published - 2004|
|Event||2004 AIChE Annual Meeting - Austin, TX, United States|
Duration: Nov 7 2004 → Nov 12 2004
|Conference||2004 AIChE Annual Meeting|
|Period||11/7/04 → 11/12/04|