TY - GEN
T1 - Preparation and characterization of bioactive and breathable polyvinyl alcohol nanowebs using a combinational approach
AU - Turaga, Uday
AU - Singh, Vinitkumar
AU - Gibson, Anna
AU - Maharubin, Shahrima
AU - Korzeniewski, Carol
AU - Presley, Steven
AU - Smith, Ernest
AU - Kendall, Ronald J.
AU - Ramkumar, Seshadri
N1 - Funding Information:
Seshadri Ramkumar gratefully acknowledges financial support from The CH Foundation, Lubbock, TX, USA. The authors are very thankful to Nathan H. Sheets, from Nature Nate Farms, for graciously providing the honey used in this study. We sincerely thank Bo Zhao at Texas Tech University (Lubbock, TX, USA) for all her help with SEM imaging of nanowebs. Thanks also to the University Arts & Sciences EOX Imaging Facility, Texas Tech University, instrument funded by NSF MRI 04-511.
PY - 2016/10
Y1 - 2016/10
N2 - Electrospun polyvinyl alcohol (PVA) nanowebs treated with a mixture of honey and polyhexamethylene biguanides (PHMBs, commercially available as Reputex 20) were prepared and characterized to evaluate their applicability in wound dressing applications. Fourier transform infrared spectroscopy was used to confirm the incorporation of functional moieties from honey and Reputex 20 into electrospun PVA nanowebs. Functionalized PVA nanowebs were characterized by evaluating their antimicrobial properties, moisture vapor transport characteristics (breathability), and tensile properties. PVA nanowebs treated with a mixture of honey and PHMBs have shown good antimicrobial activity. Additionally, functionalized PVA nanowebs have shown adequate breathability characteristics, a much needed attribute in textile materials used in wound dressing applications. Nanowebs fabricated from biocompatible polymers such as PVA, and functionalized in a combinational fashion, could be used in many different biomedical applications, including wound healing bandages and cell or tissue culture scaffolds.
AB - Electrospun polyvinyl alcohol (PVA) nanowebs treated with a mixture of honey and polyhexamethylene biguanides (PHMBs, commercially available as Reputex 20) were prepared and characterized to evaluate their applicability in wound dressing applications. Fourier transform infrared spectroscopy was used to confirm the incorporation of functional moieties from honey and Reputex 20 into electrospun PVA nanowebs. Functionalized PVA nanowebs were characterized by evaluating their antimicrobial properties, moisture vapor transport characteristics (breathability), and tensile properties. PVA nanowebs treated with a mixture of honey and PHMBs have shown good antimicrobial activity. Additionally, functionalized PVA nanowebs have shown adequate breathability characteristics, a much needed attribute in textile materials used in wound dressing applications. Nanowebs fabricated from biocompatible polymers such as PVA, and functionalized in a combinational fashion, could be used in many different biomedical applications, including wound healing bandages and cell or tissue culture scaffolds.
UR - http://www.scopus.com/inward/record.url?scp=84994700832&partnerID=8YFLogxK
U2 - 10.32964/tj15.10.655
DO - 10.32964/tj15.10.655
M3 - Article
AN - SCOPUS:84994700832
SN - 0734-1415
VL - 15
SP - 655
EP - 662
JO - Tappi Journal
JF - Tappi Journal
ER -