(+)-Pinoresinol synthase: A stereoselective oxidase catalysing 8,8′-lignan formation in Forsythia intermedia

Paul W. Paré, Huai Bin Wang, Laurence B. Davin, Norman G. Lewis

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

8,8′-Lignan skeletal formation is engendered by (+)-pinoresinol synthase, an oxidase catalysing the stereoselective coupling of two achiral E-conifery alcohols to give (+)-pinoresinol in > 97% enantiomeric excess.

Original languageEnglish
Pages (from-to)4731-4734
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number27
DOIs
StatePublished - Jul 4 1994

Keywords

  • (+)-pinoresinol synthase
  • Stereoselective coupling
  • lignans
  • oxidase

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