TY - JOUR
T1 - Physical effects of chlorpyrifos on two stages of Xenopus laevis
AU - Richards, Sean M.
AU - Kendall, Ronald J.
PY - 2003/1/10
Y1 - 2003/1/10
N2 - The effects of a 96-h static exposure to chlorpyrifos were examined in two developmental stages of Xenopus laevis (premetamorph and metamorph). Measures of effect included body length, mass, and swimming ability. Most parameters indicate that metamorphs were more sensitive than premetamorphs. For larvae exposed as premetamorphs, body length and mass were significantly lower after exposure to 0.001 mg/L and 0.1 mg/L, respectively. Premetamorph swimming activity was increased by a concentration of 0.001 mg/L. Body length and swimming activity were the most sensitive endpoints in metamorphs, showing effects at 0.0001 mg/L. The corresponding body mass was not affected until exposure to 0.1 mg/L. Based on recent environmental data, chlorpyrifos has a 0.1-32.8% probability of exceeding a 96-h time-weighted average of 0.0001 mg/L in U.S. surface waters.
AB - The effects of a 96-h static exposure to chlorpyrifos were examined in two developmental stages of Xenopus laevis (premetamorph and metamorph). Measures of effect included body length, mass, and swimming ability. Most parameters indicate that metamorphs were more sensitive than premetamorphs. For larvae exposed as premetamorphs, body length and mass were significantly lower after exposure to 0.001 mg/L and 0.1 mg/L, respectively. Premetamorph swimming activity was increased by a concentration of 0.001 mg/L. Body length and swimming activity were the most sensitive endpoints in metamorphs, showing effects at 0.0001 mg/L. The corresponding body mass was not affected until exposure to 0.1 mg/L. Based on recent environmental data, chlorpyrifos has a 0.1-32.8% probability of exceeding a 96-h time-weighted average of 0.0001 mg/L in U.S. surface waters.
UR - http://www.scopus.com/inward/record.url?scp=0037427909&partnerID=8YFLogxK
U2 - 10.1080/15287390306461
DO - 10.1080/15287390306461
M3 - Article
C2 - 12587292
AN - SCOPUS:0037427909
SN - 1528-7394
VL - 66
SP - 75
EP - 91
JO - Journal of Toxicology and Environmental Health - Part A
JF - Journal of Toxicology and Environmental Health - Part A
IS - 1
ER -