Personalized Nutrition for Management of Micronutrient Deficiency—Literature Review in Non-bariatric Populations and Possible Utility in Bariatric Cohort

Shannon Galyean, Dhanashree Sawant, Andrew C. Shin

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Background: Bariatric surgery can effectively treat morbid obesity; however, micronutrient deficiencies are common despite recommendations for high-dose supplements. Genetic predisposition to deficiencies underscores necessary identification of high-risk candidates. Personalized nutrition (PN) can be a tool to manage these deficiencies. Methods: Medline, PubMed, and Google Scholar were searched. Articles involving genetic testing, micronutrient metabolism, and bariatric surgery were included. Results: Studies show associations between genetic variants and micronutrient metabolism. Research demonstrates genetic testing to be a predictor for outcomes among obesity and bariatric surgery populations. There is limited research in bariatric surgery and micronutrient genetic variants. Conclusion: Genotype-based PN is becoming feasible to provide an effective treatment of micronutrient deficiencies associated with bariatric surgery. The role of genomic technology in micronutrient recommendations needs further investigation.

Original languageEnglish
Pages (from-to)3570-3582
Number of pages13
JournalObesity Surgery
Volume30
Issue number9
DOIs
StatePublished - Sep 1 2020

Keywords

  • Deficiency
  • Gene
  • Gene expression
  • Nutrients
  • Obesity
  • Polymorphism
  • Supplementation

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