Abstract
Background: Bariatric surgery can effectively treat morbid obesity; however, micronutrient deficiencies are common despite recommendations for high-dose supplements. Genetic predisposition to deficiencies underscores necessary identification of high-risk candidates. Personalized nutrition (PN) can be a tool to manage these deficiencies. Methods: Medline, PubMed, and Google Scholar were searched. Articles involving genetic testing, micronutrient metabolism, and bariatric surgery were included. Results: Studies show associations between genetic variants and micronutrient metabolism. Research demonstrates genetic testing to be a predictor for outcomes among obesity and bariatric surgery populations. There is limited research in bariatric surgery and micronutrient genetic variants. Conclusion: Genotype-based PN is becoming feasible to provide an effective treatment of micronutrient deficiencies associated with bariatric surgery. The role of genomic technology in micronutrient recommendations needs further investigation.
Original language | English |
---|---|
Pages (from-to) | 3570-3582 |
Number of pages | 13 |
Journal | Obesity Surgery |
Volume | 30 |
Issue number | 9 |
DOIs | |
State | Published - Sep 1 2020 |
Keywords
- Deficiency
- Gene
- Gene expression
- Nutrients
- Obesity
- Polymorphism
- Supplementation